Richard S Finkel Selected Research

Glucocorticoids

1/2019	Vamorolone trial in Duchenne muscular dystrophy shows dose-related improvement of muscle function.
10/2018	Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug.
5/2015	Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial.

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Richard S Finkel Research Topics

Disease

29	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2022 - 08/2007
26	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 12/2022 - 01/2008
4	Disease Progression 01/2021 - 04/2016
3	Inflammation (Inflammations) 01/2021 - 09/2014
3	Muscular Diseases (Myopathy) 01/2019 - 04/2013
2	Fibrosis (Cirrhosis) 06/2022 - 01/2021
2	Vomiting 01/2022 - 01/2019
2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2022 - 01/2019
2	Fever (Fevers) 01/2021 - 01/2019
2	Insulin Resistance 01/2019 - 10/2018
2	Nasopharyngitis 01/2019 - 05/2015
2	Headache (Headaches) 01/2019 - 05/2015
2	Peripheral Nervous System Diseases (PNS Diseases) 11/2015 - 04/2013
2	Muscular Dystrophies (Muscular Dystrophy) 04/2013 - 06/2002
2	Metachromatic Leukodystrophy (Sulfatide Lipidosis) 02/2011 - 11/2008
1	Hypersensitivity (Allergy) 12/2022
1	Scleroatonic muscular dystrophy 06/2022
1	Pneumothorax 06/2022
1	Airway Obstruction (Choking) 06/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Parkinson Disease (Parkinson's Disease) 01/2022
1	Asymptomatic Diseases 01/2022
1	Frontotemporal Dementia (Semantic Dementia) 01/2022
1	Intellectual Disability (Idiocy) 01/2022
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022
1	Hydrocephalus (Hydrocephaly) 01/2021
1	Growth Disorders 01/2020
1	Hirsutism 01/2020
1	Weight Gain 01/2020
1	Fatigue 10/2019
1	Distal Myopathies (Distal Muscular Dystrophy) 10/2019
1	Constipation 01/2019
1	Bone Resorption 10/2018
1	Rare Diseases (Rare Disease) 04/2016
1	Nemaline Myopathies (Nemaline Myopathy) 06/2015
1	Inborn Genetic Diseases (Disease, Hereditary) 03/2014
1	Cleft Palate (Palate, Cleft) 04/2013
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 04/2013
1	Infections 02/2013
1	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2013
1	Neuromuscular Diseases (Neuromuscular Disease) 01/2013
1	Spinal Muscular Atrophies of Childhood (Werdnig Hoffman Disease) 10/2012
1	Cardiomyopathies (Cardiomyopathy) 08/2011
1	Glycogen Storage Disease Type II (Pompe's Disease) 08/2011
1	Dmd-Associated Dilated Cardiomyopathy 12/2009

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2002
12	nusinersenIBA 01/2022 - 12/2016
9	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2012
5	ZolgensmaIBA 01/2022 - 01/2021
5	Nonsense Codon (Nonsense Mutation)IBA 10/2020 - 09/2010
5	DystrophinIBA 04/2015 - 01/2008
4	edasalonexentIBA 01/2022 - 01/2019
4	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 09/2014
4	VBP15 compoundIBA 01/2022 - 10/2018
4	Pharmaceutical PreparationsIBA 01/2021 - 12/2016
4	atalurenIBA 10/2020 - 09/2010
3	GlucocorticoidsIBA 01/2019 - 05/2015
3	salicylhydroxamic acid (SHAM)IBA 01/2018 - 12/2016
3	idebenoneIBA 01/2017 - 05/2015
2	CollagenIBA 06/2022 - 10/2019
2	Prednisone (Sone)FDA LinkGeneric 01/2022 - 01/2020
2	deflazacortIBA 01/2022 - 01/2020
2	reldesemtivIBA 07/2021 - 01/2021
2	RNA Precursors (Precursor, mRNA)IBA 12/2016 - 04/2015
1	chenodeoxycholate sulfate conjugate (CDCS)IBA 12/2022
1	Glutamine (L-Glutamine)FDA Link 01/2022
1	Amyloid (Amyloid Fibrils)IBA 01/2022
1	Dosage Forms (Dosage Form)IBA 01/2022
1	Transaminases (Aminotransferases)IBA 01/2021
1	TroponinIBA 01/2021
1	Antisense OligonucleotidesIBA 01/2021
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2019
1	NF-kappa B (NF-kB)IBA 01/2019
1	Sertraline (Zoloft)FDA LinkGeneric 01/2019
1	SteroidsIBA 05/2018
1	Investigational DrugsIBA 01/2017
1	Myelin P0 Protein (Myelin Protein Zero)IBA 11/2015
1	DNA (Deoxyribonucleic Acid)IBA 03/2014
1	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 04/2013
1	Carrier Proteins (Binding Protein)IBA 04/2013
1	Transforming Growth Factors (Transforming Growth Factor)IBA 04/2013
1	NAD (NADH)IBA 04/2013
1	Blood Proteins (Serum Proteins)IBA 01/2013
1	Messenger RNA (mRNA)IBA 01/2013
1	Hexosaminidases (Hexosaminidase)IBA 01/2013
1	Biological ProductsIBA 10/2012
1	human GAA protein (Myozyme)FDA Link 08/2011
1	AntibodiesIBA 08/2011
1	AminoglycosidesIBA 09/2010

Therapy/Procedure

10	Therapeutics 12/2022 - 01/2012
2	Palliative Care (Palliative Therapy) 02/2013 - 08/2007
2	Transplantation 02/2011 - 11/2008
1	Cell- and Tissue-Based Therapy (Cell Therapy) 12/2022
1	Intravenous Infusions 12/2022
1	Pleurodesis 06/2022
1	Chest Tubes (Chest Tube) 06/2022
1	Aftercare (After-Treatment) 06/2021
1	Oral Administration 01/2019
1	Enzyme Replacement Therapy 08/2011